Casula is located 34 kilometres south-west of the CBD , in the local government area of the City of Liverpool.
Casula is the first suburb immediately south of Liverpool on the Hume Highway and the Main Southern railway line between Sydney and Melbourne. Casula consists of undulating, gently rolling land, with elevations across the suburb being mostly between 30 and 70 metres above sea level. The Georges River forms the eastern boundary of the suburb, and its western bank is paralleled by a relatively steep escarpment.
Casula Mall is a shopping centre owned by AMP Capital and opened in 1986. It consists of a Kmart discount department store, a Coles supermarket and approximately forty specialty shops. Crossroads Homemaker Centre is another shopping centre in Casula also owned by AMP Capital. It is situated at the southern end of Casula, containing Bunnings Warehouse hardware and Costco, numerous bedding and furniture stores, electrical stores such as Bing Lee and The Good Guys.
Casula railway station is on the Inner West & Leppington and Cumberland lines of the Sydney Trains network, but it is located far from the commercial area. Relatively frequent Transit Systems bus services link Casula to the major commercial and retail centre of Liverpool and Liverpool station.